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 Formulary Chapter 4: Central nervous system - Full Chapter
04.02.01  Expand sub section  Antipsychotic Drugs
04.02.01  Expand sub section  First-Generation Antipsychotic Drugs
04.02.01  Expand sub section  Second-Generation Antipsychotic Drugs
Amisulpride (oral)
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Formulary
Amber SC
  • tablets
  • solution
  • Supported by ESCA, see link below.
 
Link  ESCA: Antipsychotics (oral)
   
Aripiprazole tablets
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Formulary
Amber SC
  • Supported by ESCA, see link below.
  • use in Tourette's syndrome approved
 
Link  ESCA: Antipsychotics (oral)
Link  NICE TA213: Aripiprazole for the treatment of schizophrenia in people aged 15 -17 years
Link  NICE TA292: Bipolar disorder (children) - aripiprazole
   
Olanzapine (oral)
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Formulary
Amber SC
  • tablets
  • orodispersible tablets
  • Supported by ESCA, see link below.
 
Link  ESCA: Antipsychotics (oral)
   
Quetiapine tablets
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Formulary
Amber SC
  • Supported by ESCA, see link below.
 
Link  ESCA: Antipsychotics (oral)
   
Quetiapine Modified-release preparations
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Formulary
Amber SC
  • Supported by ESCA, see link below.
  • Rationale for prescribing rather than first line antipsychotics to be provided with ESCA.


    APC preferred brands
    Biquelle XL, Sondate XL, Zaluron XL
    Choose most cost-effective option.
 
Link  ESCA: Antipsychotics (oral)
   
Risperidone (oral)
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Formulary
Amber SC
  • tablets
  • liquid
  • Supported by ESCA, see link below.
 
Link  ESCA: Antipsychotics (oral)
   
Clozapine tablets
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Formulary
Red
 
   
 ....
 Non Formulary Items
Lurasidone  (Latuda®)

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Non Formulary
Black
 
Paliperidone
(oral)

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Non Formulary
Black
 
Sertindole  (Serdolect®)

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Non Formulary
 
Ziprasidone  (Zeldox®)

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Non Formulary
 
Zotepine

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Non Formulary
Black
Discontinued in 2011
 
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
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Link to adult BNF
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Link to children's BNF
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Link to SPCs
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Prescribing in children

The APC notes that the informed use of unlicensed medicines or of licensed medicines for unlicensed applications (‘off-label’ use) is often necessary in paediatric practice.

The APC advises GPs to consider specialist prescribing recommendations for Green and Amber medicines that are not subject to ESCAs or RICaDs in combination with the information provided in the BNFC which goes beyond that of marketing authorisations. The BNFC has been designed for rapid reference and the information presented has been carefully selected to aid decisions on prescribing.
  

Green

Medicines suitable for routine use within primary care. Initiation and maintenance of prescribing by Specialists, GPs and other qualified clinicians.   

Amber Initiation

Amber Specialist Initiation: Initiation and maintenance of prescribing by Specialists and transfer to Primary Care prescribing when appropriate. This may be supported by a RICaD, annotated within the formulary entry.  

Amber Recommended

Amber Specialist Recommendation: Initiation and maintenance of prescribing in Primary Care following recommendation from a Specialist.  

Amber SC

Amber Shared Care: Initiation and maintenance of prescribing by Specialists and transfer to Primary Care prescribing, in accordance with an ESCA, annotated within the formulary entry.  

Red

Medicines for initiation and maintenance prescribing by Specialists only.  

Black

Non-formulary Medicines which APC/Trust DTC has actively reviewed and do not recommend for use.  

Grey

Positive NICE TA and/or awaiting local clarification on place in therapy; Please contact your Medicines Optimisation team for more information.  

The term 'Specialist' refers to Consultants, General Practitioners and Independant Prescribers with a Specialist Interest.  

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